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Classification and functional annotation of metabolites were performed based on the Human Metabolome Database (HMDB, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) database ( Partial least squares discrimination analysis (PLS-DA) was employed to identify differentially abundant metabolites between groups, utilizing the opls function with parameters orthoI=0 from the ropls R package (v1.34)

In the aberrant crypt focus (ACF) rat model induced with 1.2 Dimethylhydrazine (DMH) at a 20 mg/kg dose, the experimental treatment group (DMH + Zingiberene at a 300 mg/kg concentration) showed decreased amount of AC in the distal region compared with the positive induction control group (81)

Distinct transcriptomic profile of small arteries of hypertensive patients with chronic kidney disease identified miR-338-3p targeting GPX3 and PTPRS

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Obesity and adverse breast cancer risk and outcome: mechanistic insights and strategies for intervention