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97,98 Parks team demonstrated that saponin extract exposure dramatically decreased miR-21-5p expression in HESCs and upregulated caspase-3 expression, which in turn promoted cell apoptosis

Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Putz B et al (2004)

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BPC 157 was administered in a form of rectal solution given through an enema container at four different dose levels: 0.25 mg/kg, 0.5 mg/kg, 1 mg/kg, and 2 mg/kg

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