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Biologic therapies work by blocking certain chemicals that cause inflammation in your intestines

10.1186/s12974-017-0917-3 70

Free radicals can hurt your body if there are too many

While most ZIPs are localized at the plasma membrane, most ZnTs are localized in the intracellular compartments, except ZnT1, which is on the cell surface, where it functions as the major pathway of zinc efflux and provides control of metal ion levels (242244)