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Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination In various brain disorders characterized by brain inflammation, including multiple sclerosis (MS), microglial cells and astrocytes are key players in neuroinflammation and can be triggered by agents like interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS)

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