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These studies linked the generation of reactive metabolites, downstream formation of covalent adducts to intracellular proteins, verification of adaptive immune response directed against respective adduct-dependent antigens, and clinical status of patients [123,124,125,126,127,128]

Like autoimmune diseases, these conditions are characterized by oxidative stress and inflammation and inappropriate release of histamine in many cases

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Antiglioma activity of 2, 2: 6, 2-terpyridineplatinum(II) complexes in a rat model-effects on cellular redox metabolism

137 SantarelliL.SaxeM.GrossC.SurgetA.BattagliaF.DulawaS.et al (2003)

Additionally, the synergistic use of docetaxel and TQ holds promise for potentially reducing the dosage of docetaxel and mitigating its associated adverse effects while maintaining therapeutic effectiveness for patients with castration-resistant prostate cancer (CRPC)