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2016;98-B(1 Suppl A):10512

PMID: 40999918 Adv Sci (Weinh) A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors

Once transported into neurons, MPP + inhibits the activity of mitochondrial complex I, leading to oxidative stress that directly causes the deformation and death of DA neurons, ultimately resulting in PD (Geng et al., 2019)