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Decreased GSH leads to a cascade of events, including an inability to mitigate oxidative stress, a subsequent increase in the release of cytokines IL-6 and TGF-, both of which are shown to further decrease GSH synthesis, and an increase in platelet activation, contributing to microclot formation

doi: 10.1016/j.biopha.2018.03.142 121 MaJDJingJWangJWYanTLiQHMoYQet al

marneffei , including glutathione biosynthetic enzymes (Gcs1 and Gcs2), glutathione peroxidase (Gpx1), glutathione reductase (Glr1), and a family of glutathione S-transferase (Gst)

In addition, the inclusion of gp42 may have shielded the immune system from neutralizing epitopes on gH/gL that preferentially neutralize EBV infection of epithelial cells such as CL40

Compared with the group administered with DEX/SERT, there was a decrease in MDA levels with DEX/SILY 140, DEX/SILY 280, DEX/SERT/SILY 140, and DEX/SERT/SILY 280