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Between these two pathways, the d-Gulose pathway uses GDP-l-Gulose formed from GDP-d-mannose ( Figure 2 ), whose formation follows the same route as described in the d-mannose/l-galactose pathway for AsA production ( Figure 2 ), where glucose is used for the production of myo-inositol, which through other steps will be converted into the precursor l-GulL (Lorence et al., 2004)

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doi: 10.1016/j.cell.2024.05.031 158 WuJ.LiuQ.ZhangX.TanM.LiX.LiuP.et al

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non-selective elution methods are used in combination with highly specific ligands

Cells retained the capacity to differentiate into KRT4 + suprabasal cells, although this was reduced at 12 months (Fig