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In patients with PF, the progression of fibrosis is believed to be influenced by three primary factors: excessive epithelial damage caused by inhaled pollutants, senescence, and genetic susceptibility [32]

So its safety and effectiveness in humans remain uncertain

The role of angiogenesis regarding to the growth of primary tumors along with their metastasis to remote organs is well established (Thaloor et al., 1998)

Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion

Guerquin, M

Roos I, Sharmin S, Lechner-Scott J et al (2022) Comparison of the effectiveness of ocrelizumab vs interferon , fingolimod and natalizumab on relapses in RRMS