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Tripartite motif-containing 37 (TRIM37) promotes the aggressiveness of non-small-cell lung cancer cells by activating the NF-B pathway: TRIM37 promotes the aggressiveness of NSCLC

Zeng Z, R-Y W, Shi Y, Qiu YH, Mak DH, Coombes K, Yoo SY, Jessen K, Liu Y, Rommel C, Kantarjian HM, Kornblau SM, Fruman D, Andreeff M , Konopleva M

Our observations of a concentration-dependent inhibition of NFT-dependent glutathione synthesis stimulation (Fig

Alternatively, compounds capable of disrupting the oligomerization of cancer-relevant TRIMs would be expected to block their action, since the higher-order assembly of TRIMs is thought to be essential for their function

The number of days of acute lung injury decreased in NAC group, yet mortality rate did not change significantly between groups

When they combine with estrogen fluctuations, the effect multiplies