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Kosower et al [11] had previously reported that monobromobimane (a derivative of 1,5-diazobicyclo[3,3,0] actadiendiones) and non fluorescent compound with an electrophilic site, slowly reacted with glutathione to form fluorescent glutathione conjugate and that the reaction might be catalysed by glutathione transferase

Its involvement adds an epigenetic layer to neuronal vulnerability, potentially driving the progressive neuronal loss observed in conditions such as AD [154, 155]

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DFO, on the other hand, has a higher molecular weight compared to other chelators and is highly hydrophilic

A critical review of the capsaicin 8% patch for the treatment of neuropathic pain associated with diabetic peripheral neuropathy of the feet in adults

Int Immunopharmacol 118:110047 Long T, Pan W, Li F et al (2023) Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury