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Therapeutic window is the therapeutic dose between the minimum amount of and the maximum amount of a pharmaceutical drug that will prevent or reduce the risk of occurrence of the biological or medical event that is sought to be prevented in a tissue, a system, animal or human by a researcher, veterinarian, medical doctor or other clinician

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PFs as a versatile strategy against diverse broiler stressors Heat stress: the primary noninfectious challenge Heat stress (HS) causes physiological problems in broilers through the overproduction of reactive oxygen species (ROS) and a significant inflammatory response

Control Release 377 , 239255 (2025)

Thus, the translational regulation of HIF-1 independent of oxygen primarily involves the phosphorylation of ribosomal protein S6 (RPS6) and the eukaryotic initiation factor 4F (eIF4F), similar to the translational regulation of other proteins

The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors navitoclax (ABT-263) and ABT-199