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Cholesterol influences the redox status of hepatocytes and contributes to oxidative stress, thereby promoting liver injury and cellular toxicity

By incorporating immune adjuvantssuch as cytokines, checkpoint inhibitors, or STING agonistswithin the hydrogel matrix, these systems deliver therapeutics directly to the tumor microenvironment, reprogramming immunosuppressive niches into immunostimulatory hubs [172]

Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development

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Trseid, M., Andersen, G

Statistical analysis The sensitivity and post-hoc power calculations were performed using standard two-sample t-test formulas and the G*Power 3.1 software for sample size calculation 36