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Description

C.ChalmersJ

remodeling of metabolite networks (SCFAs, secondary bile acids, indole derivatives) with downstream signaling through G-proteincoupled receptors, FXR/TGR5, and the aryl hydrocarbon receptor

Research has shown that vitamin D can enhance the muscle protein synthesis rate, particularly when combined with other anabolic factors like insulin and HMB [15]

When used as a treatment, it is administered via intravenous infusion for a few days during each chemotherapy cycle, although the dosing regimen has varied in clinical trials (Loprinzi, Hershman 2020)