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Future work should further deepen research into cell death mechanisms (especially pyroptosis and ferroptosis) and inflammatory/oxidative stress pathways, refine preclinical models to better mimic human conditions, and conduct large-scale clinical cohort studies to validate potential therapies

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(2023) 11:CD008176

Simulations suggested that this microsphere formulation could allow for once-monthly human dosing while maintaining effective drug levels, potentially reducing adverse side effects

doi: 10.1016/j.fsi.2022.09.065

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