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In endothelial cells, elevated indoxyl levels cause oxidative stress, a pro-inflammatory response, and increased adhesion molecule expression

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Alleviating oxidative stress Oxidative stress refers to an imbalance between oxidation and antioxidation processes in cells, leading to increased ROS, which consequently triggers chain reactions that damage DNA, proteins, lipids and other biomolecules, ultimately resulting in biological dysfunction (201)

[DOI] [PubMed] [Google Scholar] 223.Bonaz B

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It works by increasing levels of dopamine and norepinephrine in the brain, which helps improve focus, attention, and impulse control in people with ADHD