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[PubMed: 16594907] 12

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The cysteinylglycine formed in the transpeptidase reaction is split by dipeptidase (Reaction 6)

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One exciting new frontier in the action of natural products is that they have the ability to cause ferroptosis by causing iron overload and lipid peroxidation, or through the modulation of glutathione metabolism and inhibition of GPX4, thus opening a promising direction to target chemoresistant OC cells with an apoptotic-resistant phenotype (Na et al., 2024

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Cell Death Dis, 2022, 13: 763 Perron NR, Brumaghim JL

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