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doi: 10.1080/09513590.2016.1203893 212 OktemMOzcimenEEUckuyuAEsinlerIPamukBBayraktarNet al

These trials, which are primarily in Phases I or II, aim to determine maximal tolerable dose, dose-limiting toxicities, antitumor efficacy, as well as pharmacokinetics and pharmacodynamics of these ruthenium compounds