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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochem Pharmacol , 2018;147:141-152

10.1016/j.bbrep.2023.101476 56 IncalzaM

Among all participants, the use of individual vitamin B 12 supplements with a daily dose range between 100 and 5000 mcg was a significant positive predictor of milk vitamin B 12 concentration

The cut-off between normal vitamin B12 levels and deficiency varies by method and laboratory, but most laboratories define subnormal serum or plasma values as those lower than 200 or 250 pg/mL (148 or 185 pmol/L)

Across the board, the figures tell a consistent story: this is not a rare finding

While more studies are needed, one thing is clear: we now have a bigger toolbox for fighting obesity