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Aging is accompanied by BBB breakdown, and instead of being region-specific as in neurological diseases (e.g., hippocampus in Alzheimers disease), it is zonation-specific (capillaries are more affected than other vessel types) (Zhao et al., 2020)

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rILYd4, a human CD59 inhibitor, enhances complement-dependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia

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Methionine, inositol, and choline are cofactors in hepatic lipid metabolism