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Eur J Medicinal Chem Rep

In this way, MDM2 enables the development of tumours that retain wild-type p53

Moreover, another antifungal agent, clotrimazole, can inhibit cancer cell division and proliferation by blocking the entry of calcium and potassium ions into the cells ( The third-generation EGFR inhibitor osimertinib (OSI) has a dual function

doi: 10.1016/j.omto.2020.01.003 70

Selenoproteins and protection against oxidative stress: Selenoprotein N as a novel player at the crossroads of redox signaling and calcium homeostasis

Including ( a ) H3K14ac global peaks, ( b ) H3K4me1 global peaks, ( c ) H3K4me2 global peaks, ( d ) H3K27ac global peaks (adopted from Encode ENCFF544LXB), ( e ) Intersected peaks of H3K4me1 and H3K14ac, ( f ) Intersected peaks of H3K4me2 and H3K14ac, ( g ) Intersected peaks of H3K27ac and H3K14ac, and ( h ) Intersected peaks of LSD1 and H3K14ac (only showing H3K4me1 and H3K4me2)