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10.1038/nature06187 Nature 58 LamK.ArayaR.HuangA.ChenQ.Di ModicaM.RodriguesR.et al (2021)

Licochalcone A upregulates GPX4, downregulates ACSL4, and inhibits the Nrf2/HO-1 pathway in a cardiac ischemia/reperfusion model in SD rats (Lin et al., 2023)

So when taking any medicine, it's always a good practice to familiarize yourself with its risks and warnings

the underlying cellular environment, oxidative stress, mitochondrial function, and detoxification capacity, shapes how you age and how well you respond to every other treatment