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A single 100 mg vial contains more elemental copper than the oral Tolerable Upper Intake Level for an entire day and roughly 30 to 50 times the daily copper dose that clinicians deliver intravenously to patients on total parenteral nutrition, where copper is dosed conservatively precisely because the parenteral route bypasses gut regulation

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To test the model, the researchers plan to treat overdosed mice with different relative concentrations of NAC and glutamine -- which the liver converts to glutamate -- to see which dosing combinations maximize their survival