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Imprecision of results through unfavorable distribution of confidence intervals, risk of bias, heterogeneity (as indicated by a higher I 2 ), differing types of intervention, and their length (in recovery-associated studies) and potential publication bias as indicated by a significant Eggers test can also be constituted as downgrades

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Ionizing radiation from radiation therapy also induced HIF-1 accumulation, which resulted in nuclear translocation of SLC7A11 and inhibited ferroptosis in HCC (138)

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