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Consistently, in RPE and retinal cell models, PEDF secretion is stimulated by extracellular zinc and is associated with Zn 2+ -induced apoptosis (Fig

298 Homologous protein transcription factors inhibit the expression of LINE1 in adult dopaminergic neurons 299 and prevent its degeneration

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Tardive dystonia: The image on the left shows eyelid spasms (blepharospasm), spasm of jaw closure (jaw dystonia), and mouth pursing

Several studies indicate that human cells can also actively trigger ROS production at small doses, as part of signaling pathways, regulating cell survival and proliferation, as a defense mechanism against invaders (Sena and Chandel, 2012)

25 Moreover, Wu et al