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However, orthopaedic-specific clinical evidence supporting improved healing or postoperative recovery is lacking

114 In another meta-analysis that pooled findings from eight randomized controlled trials, PNE was found to moderately reduce pain intensity but did not reduce fibromyalgia impact, catastrophizing, or anxiety

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Reference: AIC100 Aicar 100mg AICAR is an analog of adenosine monophosphate (AMP), a nucleotide that is considered to play an important role in cellular energy metabolism