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Description

It is thought to primarily interact with melanocortin 1 receptors (MC1R), which are expressed in melanocytes and considered central to pigmentation processes

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In addition, the risk of orthostatic hypotension increases in patients with various diseases associated with autonomic failure (i.e., diabetes mellitus, alcohol dependence, Parkinsons disease, multiple system atrophy, and pure autonomic failure) or presence of dehydration.[] The clinical manifestation of orthostatic hypotension can include dizziness, light-headedness, headache, visual disturbance, and generalized weakness

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