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194,195 Dysregulation of the Wnt/-catenin pathway is closely linked to the development of gastric cancer and the emergence of chemotherapy resistance

Adenocarcinoma of the Lower Esophagus with Barrett's or without Barrett's: Differences in Patients Survival After Preoperative Chemoradiation

We are currently in an internal evaluation phase, reviewing the published research and running a structured internal protocol with our clinical team

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For example, the p53 mutants p53 R 237 H and p53 R 175 H promote sensitivity to ferroptosis-like cell death, most likely through the combination of p53 mutants with NRF2 and through the suppression of the NRF2-dependent transactivation of SLC7A11 together with other antioxidant genes that oppose ferroptosis (Sasaki et al., 2002