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Immunohistochemistry images revealed a clear increase in GLUT1 expression in both the ileum and colon of metformin-treated mice (Fig

They perform a variety of roles in eukaryotes but share the common function of ROS generation by innate immune cells in response to pathogens

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RIG-I (DDX58) interacts with MDA-5 and utilizes the mitochondrial adapter protein Cardif (IPS-1) to upregulate the expression of BH3-only proteins Puma and Noxa, thereby promoting intrinsic apoptosis in melanoma cells [162]