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Wang J, Xiao M, Wang J, Wang S, Zhang J, Guo Y, et al

While niacin supplementation can improve muscle mass and positively impact lipid profiles 15 in mitochondrial disease patients and healthy population, it has been also associated with hyperglycemia 28

Metformin: a potential therapeutic tool for rheumatologists

Subsequently, total DNA was extracted from the cells, and the relative expression level of cytochrome c oxidase 1 (mtCO1) was analyzed through PCR to serve as a reference for measuring mitochondrial DNA content