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These situation apply to G6PD mutants that cause the most severe clinical phenotypes (that of CNSHA, as will be discussed later)

6.2 Sample size and study design Another restricition exists in the comparatively small sample scale and heterogeneity of study designs in clinical trials

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10.1007/s00586-014-3305-z 240 RoughleyP

IGF-2R plays a dual role in AD pathology