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Arch Dis Child (2016) 101(1):96100

This process is regulated by ESCRT-dependent and non-ESCRT-dependent mechanisms involving tetraspanins [30]

Studies have mainly explored the regulatory effects of AS-IV on fibrosis from the perspectives of experimental animal models at the cellular, molecular and genetic levels, with most only focusing on single drug components and large-sample placebo-controlled, randomized and standardized double-blind experimental data regarding TCM treatments awaiting further investigation (10,14)