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The Trx-based system also regulates redox-sensitive transcription factors such as p53, which, when activated by oxidative stress, supports cell survival mechanisms in conditions with high ROS

In: Gupta DK, Palma JM, Corpas FJ (eds) Reactive oxygen species and oxidative damage in plants under stress

R., Vieta, E

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These results, combined with the observed inhibition of the Toll-like receptor signaling pathway and the NF-B signaling pathway, indicate that the TLR2/4-NF-B signaling pathway plays a crucial role in mediating the alleviation of oxidative stress-induced inflammatory damage by astaxanthin

Arjomandy B, Balter P, Zhang X, Chang JY