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Coronary and arterial plaque (atherosclerosis) develops gradually as cholesterol particles such as LDL in the blood are "lipid oxidized" and damage the blood vessels' lining, forming a plaque

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This can occur in people of any agefrom infants to the elderly

Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy

Increased expression of toll-like receptor 2 in rat diabetic nephropathy