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USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-beta2 transcription

H NMR (200 MHz, CDCl 3 ) d 4.77 (ddd, J = 13.6, 9.1, 4.6 Hz, CHONO 2 , 1H), 3.61 (ddd, J = 13.6, 9.1, 4.6 Hz, CHOH, 1H), 2.89-2.84 (m, OH, 1H), 2.20-2.10 (m, CH 2 , 2H), 1.80-1.50 (m, CH 2 , 2H), 1.49-1.20 (m, CH 2 , 4H)

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Despite decades of intensive research, the exact mechanisms driving the onset and progression of AD remain incompletely understood, underscoring the urgent need for continued investigation into its pathophysiology and the development of effective therapeutic interventions (Korczyn and Grinberg, 2024)