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Intestinal barrier transport is enhanced, and solubility is increased by these carriers [36]

Additionally, tobacco consumption changes the composition of the microbiota in the gut in a way that mitigates intestinal inflammation, and then leads to less misfolding of the protein -Syn in enteric nerves, reducing the risk of PD by minimizing propagation of the protein aggregates to the central nervous system (CNS) (Wood, 2017