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Finally, cytotoxic events induced by cisplatin were evaluated in HK-2 cells with and without various inhibitors

This is relevant as highly acidic solutions are damaging to the bladder

In a study employing OGD/R models of BV2 cells, the intervention of vitamin K1 attenuated retinal inflammatory responses by moderating microglial ferroptosis, which was characterized by increased level of GPX4 and SLC7A11 (45)

Here, we see that 5FU can induce changes in mitochondrial abundance in HCT116 cancer cells but fails to induce similar changes in hMSCs, evidenced by NAO staining and protein expression (Extended Data Fig

IGF-1 LR3 acts more directly on tissue IGF-1 receptors and has a much longer activity window, but its human safety and efficacy data are essentially absent

Inhibition of metabotropic glutamate receptor 5 facilitates hypoxia-induced glioma cell death