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Therefore, a rise in Tfr cell levels in both peripheral blood and BALF in sarcoidosis may be a compensatory response necessary to curb inflammation at the site of the tissue lesion, where Tfr cell functional activity may not be as effective, which could contribute to pulmonary fibrosis

10.1172/JCI131859 147 OkabeS.TanakaY.GotohA

Zhang L, Meng W, Chen X, Wu L, Chen M, Zhou Z, Chen Y, Yuan L, Chen M, Chen J, Shui P

10.1111/jocn.16120 196

Therefore, PEGylation now plays an important role in drug delivery, especially of peptide and protein based drugs, thus increasing their potential as therapeutic agents [11]

To view a copy of this licence, visit About this article Cite this article Gharib, F.A.E.L., Osama, k., Sattar, A.M.A.E