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Tretinoin is an FDA-approved retinoid with the strongest clinical evidence for photoaging

Bottom line: sermorelin has more historical clinical evidence than most peptides discussed in research-use forums, but modern adult evidence is thin

For men with functioning pituitary glands and sub-optimal GH output but not frank AGHD Sermorelin or CJC-1295 can stimulate more GH release through the bodys own machinery

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