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The other drawback is vial longevity

Compared to microgels, microspheres have the advantage of slow long-term drug release (Figure 3)

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However, the tests employing both 14 Carbon or 13 Carbon labeled cobalamin require more validation to diagnose B12 malabsorption in clinical patients (Miller & Green, 2020)

Supports Circadian Rhythm : Helps to regulate sleep-wake cycles, promoting a healthier daily rhythm