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immune dysregulation has been linked to ME/CFS patients (201, 255) ( Table 2 ) ( Figure 11 ), it is possible that infectious organisms result in chronic symptoms by interfering with host gene expression, immunity, and metabolism (25)

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10.3389/fphys.2017.00600 Front Physiol

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Researchers should note that DSIPs receptor and complete mechanism of action remain formally uncharacterised this pharmacological ambiguity is accurately reflected in the published literature and should be considered in experimental design