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Access this article Similar content being viewed by others Data Availability The authors confirm that the data supporting the findings of this study are available within the article

Human trials in neurodegeneration and other oxidative-stress conditions have been largely inconclusive despite strong mechanistic rationale, and no glutathione product is established as a treatment for any of these diseases

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10.1136/pgmj.39.452.348 15

The authors also validated that GSH content and GPX4 activity were significantly decreased when H22 cells were co-incubated with Mn-MOF (Figures 5H, I)