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Description

Nicassio L, Fracasso F, Sirago G, et al

These were secondary, explorative outcome variables, and the number of patients to evaluate by the iohexol plasma clearance technique and hyperinsulinemiceuglycemic clamp was not calculated a priori on the basis of an expected treatment effect, but was dictated by feasibility, considering that both procedures are time- and cost-consuming and demanding for both patients and investigators