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Notably, gastric cancer specimens with fungal colonization exhibit concomitant upregulation of PD-L1 expression, suggesting fungal-mediated immune evasion through checkpoint protein induction (Zhang et al., 2022)

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5.2 The significance of redox homeostasis in cancer development and progression Redox homeostasis is the dynamic balance between reactive oxygen species (ROS) generation and antioxidant defense also is profoundly disrupted in cancer and serves as a central driver of tumor development, progression, and metastasis

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In short, breast cancers multifaceted nature arises from a complex interplay of genetic and environmental factors, leading to various molecular subtypes with distinct pathophysiologies

Praziquantel for schistosomiasis: Single-drug metabolism revisited, mode of action, and resistance