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However, the impact of CoQ 10 alone without the other supplements was not directly assessed

J.Puzio-KuterA

Chris : Linus Pauling Institute has some really good data on this question

doi: 10.1093/eurheartj/ehab115

A major modulating factor is the regulation of BRAF V600E expression and whether it is driven by an exogenous or the endogenous promoter, which presumably causes variance in expression levels of the mutant kinase leading to differential signaling strengths