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Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing

In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12

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Many peptides are supplied in lyophilised powder form

That means your body can draw from these stores for years before you start to show signs of a deficiency