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RNS-induced pre-degenerative dysfunction of dopaminergic neurons NO-mediated alterations axo-dendritic function As discussed above, nNOS contains a PDZ domain that confers binding capacity to many post-synaptic density-proteins (e.g., PSD93/95, PFK-M, CAPON, and syntrophin) and is therefore regionally distributed along synaptic spines

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Thus, the present study provides clear evidence that, at least in Nile tilapia, dietary l-carnitine is physiologically utilised in the transport of acyl-carnitine into mitochondria and improves FA utilisation, while dietary d-carnitine appears to be treated as a xenobiotic and disrupts metabolism