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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Northrop-Clewes C.A., Thurnham D.I

10.1021/ja062927q

FEBS Lett 581:43714376 Vieira Dos Santos C, Rey P (2006) Plant thioredoxins are key actors in the oxidative stress response

Examination of the human X-ray crystal structure suggests that this residue (Glu352 in the human enzyme), which is buried deep within the TIM barrel domain, may be important for stabilization of the tertiary structure of the enzyme

Despite a prompt therapeutic regimen consisting of thiamine (37.5 mg/kg) and biotin (10 mg/kg) twice daily, the patients conditions never improved and he died at 4 months of age

Understanding the interplay between GBM and MDSCs provides a compelling basis for therapeutic interventions