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Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis

GS is transcriptionally regulated by STAT5 and highly expressed in radiation-resistant NPC cells

Acta 1860 , 12021210 (2016)

& Nakov, L

revealed that overexpression of GPX4 inhibits IL-6-induced activation of the JAK1/STAT3 signaling pathway in VSMCs, thereby reducing the recruitment and polarization of pro-inflammatory macrophages