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Preliminary findings from these ongoing trials have shown that utilizing glutathione precursors (like high-dose N-acetylcysteine) successfully restores these brain glutathione levels, reduces markers of central nervous system oxidative stress, and significantly ameliorates the clinical symptoms of ME/CFS

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5UTR refers to those GpGs within the 5 untranslated region, between the TSS and the ATG start site

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The used modes of administration (systemic and/or subcutaneous) are both relevant for routine administration to preterm infants, if/when ongoing clinical trials are successful (ClinicalTrials.gov Identifiers NCT03253263 and NCT01096784, using systemic infusion)

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